A trio of Brits, Johanna Konta, Harriet Dart and Dan Evans, will all bid for places in the fourth round while Andy Murray and Serena Williams will start their mixed doubles campaign on a sensational Saturday at Wimbledon.
The British trio in the singles draws all feature across Centre Court and No 1 Court with the power duo of Murray and Williams set to begin their partnership together after their Friday evening start time was postponed.
Konta will take to the No 1 Court stage second against the ninth seed Sloane Stephens with Evans following on and meeting Portugal's Joao Sousa.
The seasoned professionals of Williams and Roger Federer will complete the line-ups across the two main courts when they face Julia Goerges and Lucas Pouille respectively.
The middle Saturday at Wimbledon is always known for the vast array of sporting legends that are invited to Centre Court and all should be treated to an outstanding day as the Championships charge on at pace.
Nadal’s clash with Kyrgios was the talk of the town on Thursday and the three hour, four minute match delivered on every angle possible.
The 'spark' between the two burned throughout and that took the Spaniard to a level of animation that we've rarely seen from him in the second round.
His best tennis also arose as a result and Saturday's opponent Jo-Wilfried Tsonga, a two-time semi-finalist at The All England Club, may just approach their encounter with a touch of trepidation.
Nadal holds a 8-4 lead in their head-to-head record and won their only grass-court match at Queen's Club in 2011.
The world No 2, seeded third in SW19, is focused, passionate and should be too experienced to suffer a dip in form despite reaching such an emotional high against Kyrgios.
Stephens is seeded ninth in the competition and on paper could struggle against the British No 1 Konta.
Konta, who is seeded 19th, has won all three meetings with the 26-year-old and the trio of matches have all come this year.
Mostly recently, they clashed in the quarter-finals of the French Open and a breezy 6-1 6-4 victory belonged to the Brit.
Stephens has not reached the last eight of Wimbledon in six years but Konta herself has made everyone aware that she's taking her opponent seriously.
Of the Dart, Konta and Evans trio, the youngest has the most formidable challenge ahead of her when it comes to her face-off against Barty.
The Brit has hailed the match-up as "super exciting" and cited it as a great opportunity to go out there with nothing to lose.
Her Australian opponent made a real statement of intent with a demolition of Alison van Uytvanck. Her 6-1 6-3 victory arrived in 55 minutes and extended her winning-run out to 14 matches in a row.
As mentioned for Konta, it's an encounter with Stephens and the Brit has looked rock solid so far in the Championships.
The British No 1 has already dispatched Ana Bogdan and Katerina Siniakova and has served imperiously thus far, her fans will want to see more of the same on the No 1 Court.
Evans' straight sets second-round victory over 18th seed Nikoloz Basilashvili clearly meant the world to him and he's on the verge of breaking back into the top 50.
The professionalism with which he's now approaching his tennis, and his game on court, has produced an assured time on the grass and Sousa will know that he's meeting a man who is in form and hungry for more.
In the doubles, of course it's all about Murray and Williams. The most-anticipated pairing of the Championships will take to court together not before 5.30pm and will meet Andreas Mies and Alexa Guarachi.
Earlier, Murray will try and pick up where he left off with Pierre-Hugues Herbert, as they play a second round men's doubles match out on No 2 court.
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